AICM USMLE Step 1 Lecture Topics



First of all, Happy New Year people.  It's been a crazy past year for me as the Bonaire to USA transition; on top of that with only three week break after finishing Bonaire I started AICM right away in January 2011 and finished it in April 2011.

I know AICM is on the minds of MD3 and MD4 and so I'm trying to gather a lot of information about it and luckily I stumbled on information about it.  As you scrolled down you will see the topics in detail on what to expect when you attend the USMLE Step 1 lectures in AICM in Chicago.  Also, the following may seem overwhelming, but once you go through it once it's not that bad.

Biochemistry and Molecular Biology
  • Gene expression: DNA structure, replication, and exchange, transcription, translation, including defects.
  • Structure and function of proteins
  • Metabolic pathways of small molecules and associated diseases
  • Biosynthesis and degradation of other macromolecules and associated abnormalities, complex
  • Carbohydrates glycoproteins, and proteoglycans

Human development and Genetics
  • Embryogenesis: programmed gene expression, tissue differentiation and morphogenesis, homeotic genes, and developmental regulation of gene expression
  • Congenital abnormalities: principles, patterns of anomalies, dysmorphogenesis
  • Principles of pedigree analysis, including inheritance patterns, occurrence and recurrence risk determination
  • Population genetics: hardy-Weinberg law, founder effects, mutation-selection equilibrium genetic mechanisms: chromosomal abnormalities, mendelian inheritance, multifactorial diseases clinical genetics, including genetic testing, prenatal diagnosis, newborn screening, genetic counseling/ethics, gene therapy
 
Behavioral Sciences, Ethics, Statistics
  • Progression through the life cycle, including birth through senescence
  • Psychologic and social factors influencing patient behavior
  • Patient interviewing, consultation, and interactions with the family
  • Medical ethics, jurisprudence, and professional behavior
  • Quantitative methods
    • Fundamental concepts of measurement
    • Fundamental concepts of study design
    • Fundamental concepts of hypothesis testing and statistical inference

Pharmacology

  • General principles of pharmacodynamic and pharmacokinetic
  • General properties of autacoids, including peptides and analogs, biogenic amines, prostanoids and their inhibitors, and smooth muscle/endothelial autacoids
  • General principles of autonomic pharmacology
  • General properties of antimicrobials, including mechanisms of action and resistance
  • General properties of antineoplastic agents and immunosuppressants, including drug effects on rapidly dividing mammalian cells

Microbiology

  • Microbial classification and its basis
  • Bacteria and bacterial diseases
  • Viruses and viral diseases
  • Fungi and fungal infections
  • Parasites and parasitic diseases

Immunology

  • Production and function of granulocytes, natural killer cells, and macrophages
  • Production and function of t lymphocytes, t-lymphocyte receptors
  • Production and function of b lymphocytes and plasma cells; immunoglobulin and antibodies.
  • Antigenicity and immunogenicity; antigen presentation; cell activation and regulation; tolerance and clonal deletion
  • Immunologic mediators: chemistry, function, molecular biology, classic and alternative complement pathways, cytokines, chemokines
  • Immunogenetics; mhc structure and function, class i, ii molecules; erythrocyte antigens
  • Immunizations: vaccines, protective immunity
  • Alterations in immunologic function
  • Immunologically mediated disorders
  • Immunologic principles underlying diagnostic laboratory tests (e.g., ELISA, complement fixation, RIA, agglutination)

Hematopoietic and Lymphoid Systems

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical injury
    • Neoplastic disorders
    • Metabolic and regulatory disorders
    •  vascular and endothelial disorders
    • Systemic disorders affecting the hematopoietic and lymphoreticular system (e.g., nutritional deficiencies, systemic lupus erythematosus)
    • Idiopathic disorders
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the hematopoietic system
    • Other therapeutic modalities

Central and Peripheral Nervous Systems

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes, including neural tube derivatives, cerebral ventricles, neural crest derivatives
    • Organ structure and function
    • Cell/tissue structure and function
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders, including primary and metastatic
    • Acquired metabolic and regulatory disorders
    • Vascular disorders
    • Systemic disorders affecting the nervous system
    • Idiopathic disorders affecting the nervous system
    • Congenital disorders, including metabolic
    • Degenerative disorders
    • Paroxysmal disorders
    • Disorders of special senses
    • Psychopathologic disorders, processes and their evaluation
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the nervous system
    • Other therapeutic modalities (e.g., radiation, CSF shunting, surgery)

Skin and Related Connective Tissue

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function, including barrier functions, thermal regulation, eccrine function
    • Repair, regeneration, and changes associated with stage of life or ethnicity
    • Skin defense mechanisms and normal flora
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders
    • Metabolic, regulatory, and structural disorders
    • Vascular disorders
    • Systemic disorders affecting the skin
    • Principles of therapeutics
      • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the skin and connective tissue, including anti-inflammatory agents emollients, sunscreen, retinoids, antimicrobial agents, cytotoxic and immunologic therapy
      • Other therapeutic modalities

Musculoskeletal System

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders
    • Metabolic, regulatory, and structural disorders
    • Vascular disorders
    • Systemic disorders affecting the musculoskeletal system (e.g., diabetes mellitus)
    • Idiopathic disorders
    • Degenerative disorders
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the musculoskeletal system
    • Other therapeutic modalities (e.g., radiation, surgery, casts, rehabilitation)

Respiratory System

  • Normal processes
    • embryonic development, fetal maturation, and perinatal changes
    • organ structure and function
    • cell/tissue structure and function, including surfactant formation, alveolar structure
    • repair, regeneration, and changes associated with stage of life
    • pulmonary defense mechanisms and normal flora
  • Abnormal processes
    • infectious, inflammatory, and immunologic disorders
    • traumatic and mechanical disorders
    • neoplastic disorders
    • metabolic, regulatory, and structural disorders
    • vascular and circulatory disorders
    • systemic disorders affecting the respiratory system
  • Principles of therapeutics
    • mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the respiratory system
    • other therapeutic modalities

Cardiovascular System

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • ell/tissue structure and function
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders
    • Metabolic and regulatory disorders
    • vascular disorders
    • Systemic diseases affecting the cardiovascular system
    • Congenital disorders of the heart and central vessels
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the cardiovascular system
    • Other therapeutic modalities

Gastrointestinal System

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function, including alimentary canal, liver and biliary system, salivary glands and exocrine pancreas, motility, and digestion and absorption
    • Cell/tissue structure and function
    • Repair, regeneration, and changes associated with stage of life
    • Gastrointestinal defense mechanisms and normal flora
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders, including benign and malignant
    • Metabolic and regulatory disorders
    • Vascular disorders
    • Systemic disorders affecting the gastrointestinal system
    • Principles of therapeutics
      • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the gastrointestinal system
      • Other therapeutic modalities (e.g., surgical procedures, stents, feeding tubes)

Renal/Urinary System

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function, including renal metabolism and oxygen consumption, hormones produced by or acting on the kidney
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders, including primary  and metastases
    • Metabolic and regulatory disorders
    • Vascular disorders
    • Systemic diseases affecting the renal system
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the renal and urinary system
    •  other therapeutic modalities (e.g., dialysis, renal transplantation)

Reproductive System

  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function, including hypothalamic-pituitary-gonadal axis, sex steroid and gestational hormones
    • Reproductive system defense mechanisms and normal flora
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders
    • Metabolic and regulatory processes
    • Systemic disorders affecting reproductive function
    • Disorders relating to pregnancy, the puerperium, and the postpartum period
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the reproductive system
    • Other therapeutic modalities affecting the reproductive system (e.g., tampons)
Endocrine System
  • Normal processes
    • Embryonic development, fetal maturation, and perinatal changes
    • Organ structure and function
    • Cell/tissue structure and function, including hormone synthesis, secretion, action, and metabolism
    • Repair, regeneration, and changes associated with stage of life
  • Abnormal processes
    • Infectious, inflammatory, and immunologic disorders
    • Traumatic and mechanical disorders
    • Neoplastic disorders
    • Metabolic and regulatory processes
    • Vascular disorders
    • Systemic disorders affecting the endocrine system
    • Idiopathic disorders
  • Principles of therapeutics
    • Mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the endocrine system


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3 comments:

Leslie said...

thank u so much for this blog it helpd me find out what i needed about sjsm

SJSM Student said...

your welcome, keep visiting this site

Usmle Review said...

Hi,

The objective of the USMLE step 1 is to evaluate your knowledge in basic sciences, as well as your ability to apply that knowledge in different medical scenarios. The USMLE step 1 ensures mastery of not only the sciences that provide a foundation for the safe and competent practice of medicine in the present, but also the scientific principles required for maintenance of competence through lifelong learning. It is a computerized test of the basic medical sciences consisting of 350 multiple-choice questions. Thanks...

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